Study on Heart and Symptom Responses to Aerobic and Resistance Exercise in Adults with Spontaneous Coronary Artery Dissection or Fibromuscular Dysplasia

What this Trial Is About

This research aims to evaluate how people with Spontaneous Coronary Artery Dissection SCAD andor Fibromuscular Dysplasia FMD respond in terms of heart and lung function, blood flow, and symptoms during different types and intensities of exercise. The study focuses on these specific conditions and seeks to understand the effects of aerobic and resistance exercises on affected individuals. Participants will complete three exercise tests separated by at least 48 hours. These include a symptom-limited cardiopulmonary exercise test involving cycling with increasing effort to exhaustion, a two-stage submaximal cycling test with moderate and heavy intensity phases, and a series of six resistance exercises such as chest press, lateral raises, abdominal crunches, planks, leg press, and weighted lunges. Each test is designed to measure responses under controlled exercise conditions. During the study, participants will have their blood pressure, perceived exertion, and blood lactate levels measured at various time points before, during, and after exercise. Questionnaires assessing functional status and physical activity will also be completed at baseline. The study monitors these outcomes to understand exercise impact and safety in this population. Participation will last through these testing periods with assessments occurring around the exercise sessions.

A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia